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[IMG]http://www.*****.com/vb/*****/statusicon/post_old.gif[/IMG] 05-20-2009, 03:42 AM رقم المشاركة : [3] DR.UMAR
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HEMATOLOGY

1- Vitamin K antagonist :
a- warfarin
b- Heparin
c- Protein C
d- Antithrombin III

2- One of the intrinsic pathway
a- factor XI
b- factor XIII
c- factor I
d- factor VII

3- Para hemophilia is the deficiency of
a- factor VIII
b- factor IX
c- factor V
d- factor VII

4- Eosinophilia is seen in :
a- food sensitivity
b- Drug sensitivity
c- Atopic dermatitis
d- all of the above

5- Multiple myeloma is a neoplastic proliferation of:
a- lymphocytes
b- Granulocytes
c- Plasma cells
d- Monocytes

6- Test for intrinsic pathway:
a- bleeding time
b- Thrombin time
c- Prothrombin time
d- Partial thromboplastin time PTT


7- Paul-Bunnel test is done to diagnose:
a- multiple myeloma
b- Hodgkin’s disease
c- Infectious mononucleosis
d- all of the above

8- increased platelet count is :
a- thrombocytopenia
b- thrombopoietin
c- thrombocytosis
d- all of the above

9- Decreased platelet count is:
a- thrombocytopenia
b- Thrombopoietin
c- Thrombocytosis
d- all of the above

10- All these are causes of thrombocytopenia except:
a- cytotoxic *****
b- Aplastic anemia
c- Hemorrhage
d- Radiotherapy

11- Prothrombin time is done to test:
a- Intrinsic pathway only
b- Extrinsic pathway only
c- Extrinsic and common pathways
d- Intrinsic and common pathways

12- Normal bleeding time by Duke’s method:
a- 2-7 minutes
b- 2-7 seconds
c- 2-4 minutes
d- 2-4 seconds

13- Normal partial thromboplastin time (PPT) is :
a- 3-4 minutes
b- 30-45 seconds
c- 12-15 seconds
d- 12-15 minutes

14- Hemophilia A is the deficiency of :
a- factor V
b- factor VIII
c- factor IX
d- all of the above

15-the most common form of leukemia in children is:
a- acute lymphoblastic leukemia
b- Chronic lymphocytic leukemia
c- Acute myeloid leukemia
d- Chronic myeloid leukemia

16- Bence-Jones protein is present in cases of:
a- chronic myeloid myeloma
b-acute myeloid myeloma
c- Hodgkin’s lymphoma
d- multiple myeloma

17- Reed-Sternberg cells are found in cases of :
a- acute lymphoblastic leukemia
b- Non Hodgkin’s lymphoma
c- Hodgkin’s lymphoma
d- Multiple myeloma

18- Normal platelet count is :
a- 150,000 to 450,000/min3
b- 400,000 to 800,000/min3
c- 4,000 to 11,000 /min3
d- 50,000 to 100,000/min3

19- Antithrombin III inhibits:
a- factor Va
b- factor VIIIa
c- factor Xa
d- all of the above

20- Heparin potentiate the action of :
a- protein C
b- protein S
c- antithrombin III
d- warfarin


21- Factor II of ***** clotting is:
a- Christmas factor
b- Fibrinogen
c- Prothrombin
d- Thromboplastin

22- One of fibrinogen group is : I V VIII XIII
a- II
b- V
c- VII
d- IX

23- Fibrinogen is converted to soluble fibrin by:
a- prothrombin
b- Thromboplastin
c- Thrombin
d- all of the above

24- Thrombopoitin control the formation of:
a- red ***** cells
b- White ***** cells
c- platelets
d- non of the above

25- Normal prothrombin time (PT) is:
a- 30-45 seconds
b- 30-45 minutes
c- 12-15 seconds
d- 12-15 minutes

26- Parasitic disease is associated with:
a- monocytosis - bacteria
b- Lymphocytosis - virus
c- Basophilia - sensitive
d- Eosinophilia

27- Philadelphia chromosome is diagnostic for:
a- acute lymphoblastic leukemia
b- Acute myeloid leukemia
c- Chronic lymphocytic leukemia
d- chronic myeloid leukemia
28- Normal fibrinogen level:
a- 150-400 gm%
b- 150-400 mg %
c- 15-40 mg %
d- 15-40 gm %

29-infectious mononucleosis is caused by:
a- echo virus
b- coxsaki virus
c- Epstein Barr virus EBV
d- Cytomegalo virus

30- Atypical lymphocytosis is seen in cases of:
a- Hodgkin’s lymphoma
b- Multiple myeloma
c- Infectious mononucleosis
d- Chronic lymphocytic leukemia

31-monospot test is done to diagnose:
a- Acute myeloid leukemia
b- Acute lymphoblastic leukemia
c- Infectious mononucleosis
d- Infectious lymphocytosis

32- The test which depend on ***** platelets & capillary fragility is:
a- prothrombin time
b- Thrombin time
c- Bleeding time
d- Clotting time

33- Fibrin is broken to fibrin degradation products by the action of:
a- Prothrombin
b- Thrombin
c- Plasminogen
d- Plasmin





34- Acute myeloid leukemia is characterized by:
a- low neutrophil alkaline phosphatase
b- Myeloblast with Auer rods
c- Neutrophil with Pleger-Huet ano****
d- all of the above

35- Plasminogen is converted to plasmin by :
a- Heparin
b-Histamine
c- Urokinase
d- Serotonin

36- Increase D-dimers and fibrin degradation products are seen in cases of:
a- Hemophilia A
b- Vitamin K deficiency
c- Diffuse intravascular coagulation
d- Von Willebrand disease

37- Activated protein C degrades:
a- factor IXa
b- Factor VIIIa
c- Factor Xa
d- Factor Xia

38- Heparin is found in
a- Neutrophil
b- Basophil
c- Acidophil
d- all of the above

39- In hemophilia A the test which will be prolonged is
a- PT
b- PTT
c- Bleeding time
d- all of the above

40- Bleeding due to overdose of heparin is managed by giving:
a- Vit K
b- Vit C
c- Vit A
d- Protamin sulphate
41- Streptokinase and staphylokinase convert:
a- Prothrombin to thrombin
b- Fibrinogen to fibrin
c- Soluble fibrin to insoluble fibrin
d- Plasminogen to plasmin

42- Test for platelet **********
a- Clot retraction
b- Platelet aggregation
c- Platelet adhesion
d- all of the above

43- Prolonged PT occurs in cases of deficiency of:
a- Factor III
b- Factor IV
c- Factor V
d- all of the above

44- normal thrombin time (TT):
a- 30-45 sec
b- 2-4 min
c- 3-9 min
d- 10-20 sec

45- cause of vitamin K deficiency:
a- Obstructive jaundice
b- Prolonged use of antibiotics
c- Inadequate intake
d- all of the above

46- Cause of Hyper- Coagulable state:
a- Aplastic anemia
b- Cytotxic *****
c- Polcythemia
d- Radiotherapy

47-Physiological cause of neutrophilia:
a- New born
b- Radiotherapy
c- Cytotoxic *****
d- Prolonged use of antibiotics
48- Leucocytosis characterized by the presence of immature cells and high neutrophil alkaline phosphatase:
a- chronic myeloid leukemia
b- Acute myeloid leukemia
c- Leukaemid reaction
d- non of the above

49- Normal coagulation time (CT):
a- 3-9 min
b- 3-9 sec
c- 30-40 sec
d- 30-40 min

50- The test which measures the clotting time of citrated plasma accelerated by the addition of a clotting factor activator (kaolin) , phospholipids and calcium:
a- coagulation time
b- Prothrombin time
c- Partial thromboplastin time
d- Thrombin time

51- The test which measures the clotting time of citrated plasma to which thromboplastin and calcium has been added:
a- thrombin time
b- Prothrombin time
c- Coagulation time
d- Partial thromboplastin time

52- The test which is widely used as a control and follow up test to control anticoagulant treatment:
a- APTT
b- PTT
c- PT
d- TT

53- A disease characterized by progressive neoplastic proliferation of immature white cell precursor:
a- acute leukemia
b- Chronic leukemia
c- Lymphoma
d- Multiple myeloma


54- The absolute lymphocyte count may be up to 300,000 or more between 70 and 90 % of white cells in the ***** film appear as s**** lymphocytes . THE CASE IS:
a- Acute myeloid leukemia
b- Acute lymphoblastic leukemia
c- Chronic myeloid leukemia
d- Chronic lymphocytic leukemia

55- Variation in red cells size:
a- Poikilcytosis
b- Anisocytosis
c- Reticulocytosis
d- Leukocytosis

56- Dark red cells with no area of central pallor:
a- Stomatocyte
b- Spherocyte
c- Acathocyte
d- Schistocyte

57- Microcytic hypochromic anemia
a- hereditary spherocytosis
b- Sickle cell anemia
c- Iron deficiency anemia
d- Vit B12 deficiency anemia

58- Target cells are seen in cases of:
a- folic acid deficiency
b- Iron deficiency anemia
c- Vit B12 deficiency anemia
d- Thalassemia

59- Red cells with elongated area of central pallor:
a- spherocyte
b- Schistocyte
c- Stomatocyte
d- Elliptocutes



60- ……………….. Symmetric, short , sharp projection from the red cells and seen in iron deficiency anemia:
a- echinocyte
b- Acanthocyte
c- Elliptocyte
d- Ovalocyte

61- ……………… is a condition in which the absorption of vit B12 is greatly impaired due to failure or marked reduction of intrinsic factor secretion:
a- fauvism
b- fanconi’s anemia
c-sickle cell anemia
d- thalassemia
e- pernicious anemia

62- Hyperchromic cells are seen in:
a- iron deficiency anemia
b- Thalassemia
c- Hereditary spherocytosis
d- Sickle cell anemia

63- A prolonged low rate of bleeding results in:
a- normochromic anemia
b- Hypochromic anemia
c- Hyperchromic anemia
d- non of the above

64- Schilling test is done in diagnosis of:
a- iron deficiency anemia
b- Pernicious anemia
c- Aplastic anemia
d- folic acid deficiency


65- Defective synthesis of either alpha or beta chains of normal hemoglobin
cause:
a- sickle cell anemia
b- Aplastic anemia
c- Pernicious anemia
d- Thalassemia

66- Neutrophils represent…………… of circulating leukocyte:
a- 2-8 %
b- 0-1 %
c- 50-70 %
d- 2-4 %

67- …………. are non nucleated, biconcave shaped cells:
a- platelet
b- Leukocyte
c- Erythrocyte
d- Macrophages

68- …………….. represent 50-70 % of total leukocytes
a- lymphocytes
b- Neutrophils
c- Monocytes
d- Eosinophilis

69- …………… have a characteristic biffed nucleus and their cytoplasm is filled with large refractile granules that stain red in ***** smear
a- neutrophils
b- Eosinophilis
c- Basophiles
d- Lymphocytes

70- The cell which is responsible for antibody production is:
a- moncytes
b- T-lymphocytes
c- B-lymphocytes = plasma cell
d- Neutrophils


71- …… is a curved cell with sharp ends seen in haemoglobinopathies (HBS)
a- sickle cell
b- Spherocyte
c- Ovalocyte
d- Stomatocyte


72- All of the following is correct about sickle cell anemia except:
a- leg ulcers
b- Gall stones
c- Enlargement of spleen
d- Attacks of pain

73- ……….. is a single, large, rounded , dark , purple remnant of nucleus
a- Heinz body
b- Howeel-Jolly body
c- Pappenheimer body
d- Cabot ring

74- Agranulocyte:
a- neutrophil
b- Lymphocyte
c- Basophile
d- Eosinophil

75- Pica ( craving to eat unusual substance such as clay or ice) is one of the symptoms of:
a- G6PD deficiency
b- Thalassemia
c- Megaloblastic anemia
d- Iron deficiency anemia

76- In …………….. there’s a decreased or absent hemosiderin in bone marrow
a- sideroblastic anemia
b- Iron deficiency anemia
c- Megaloblastic anemia
d- Hemolytic anemia

77- Chloramphenicol may cause …………. anemia in long term therapy
a- iron deficiency
b- Vit B12 deficiency
c- folic acid deficiency
d- Aplastic anemia